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Damage on lining concrete in highway tunnels under combined sulfate and chloride attack

Rongrong YIN, Chenchen ZHANG, Qing WU, Baocheng LI, He XIE

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 3,   Pages 331-340 doi: 10.1007/s11709-017-0421-y

Abstract: The combined effect from sulfate and chloride is one of the important reasons to cause the damage of liningTo investigate the effect of chloride ions on the corrosion of lining concretes under sulfate attack,XRD patterns confirmed that the existence of chloride certainly depressed the corrosion damage on the lining

Keywords： lining concrete     sulfate     chloride     compression     ultrasonic    

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Stress observation of shaft lining wall during construction and initial operation

Wen Dehua

Strategic Study of CAE 2012, Volume 14, Issue 2,   Pages 80-84

Abstract:

For searching the stress and deformation law of blended shaft-liningduring construction and initial operation, sensors were buried in interior and exterior wall of shaft-liningWith the law, we can forecast the long-term safety of shaft lining and provide scientific decision evidence

Keywords： shaft lining monitoring     thick topsoil     strain     additional force    

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Deep convolutional neural network for multi-level non-invasive tunnel lining assessment

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 2,   Pages 214-223 doi: 10.1007/s11709-021-0800-2

Abstract: In recent years, great attention has focused on the development of automated procedures for infrastructures control. Many efforts have aimed at greater speed and reliability compared to traditional methods of assessing structural conditions. The paper proposes a multi-level strategy, designed and implemented on the basis of periodic structural monitoring oriented to a cost- and time-efficient tunnel control plan. Such strategy leverages the high capacity of convolutional neural networks to identify and classify potential critical situations. In a supervised learning framework, Ground Penetrating Radar (GPR) profiles and the revealed structural phenomena have been used as input and output to train and test such networks. Image-based analysis and integrative investigations involving video-endoscopy, core drilling, jacking and pull-out testing have been exploited to define the structural conditions linked to GPR profiles and to create the database. The degree of detail and accuracy achieved in identifying a structural condition is high. As a result, this strategy appears of value to infrastructure managers who need to reduce the amount and invasiveness of testing, and thus also to reduce the time and costs associated with inspections made by highly specialized technicians.

Keywords： concrete structure     GPR     damage classification     convolutional neural network     transfer learning    

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Application of coupled XFEM-BCQO in the structural optimization of a circular tunnel lining subjected

Nazim Abdul NARIMAN, Ayad Mohammad RAMADAN, Ilham Ibrahim MOHAMMAD

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 6,   Pages 1495-1509 doi: 10.1007/s11709-019-0574-y

Abstract: XFEM-BCQO) is adopted to quantify the optimum values of four design parameters for a circular tunnel liningThe parameters are: tunnel lining thickness, tunnel diameter, tunnel lining concrete modulus of elasticityand tunnel lining concrete density.Numerical simulations of the tensile damage in the tunnel lining due to a real earthquake in the literaturecoupled approach manifested a significant capability to predict the cracks and spalling of the tunnel lining

Keywords： ovaling deformation     monte carlo sampling     XFEM-BCQO     maximum principal stress    

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Digital microfluidics: A promising technique for biochemical applications

He WANG, Liguo CHEN, Lining SUN

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 4,   Pages 510-525 doi: 10.1007/s11465-017-0460-z

Abstract:

Digital microfluidics (DMF) is a versatile microfluidics technology that has significant application potential in the areas of automation and miniaturization. In DMF, discrete droplets containing samples and reagents are controlled to implement a series of operations via electrowetting-on-dielectric. This process works by applying electrical potentials to an array of electrodes coated with a hydrophobic dielectric layer. Unlike microchannels, DMF facilitates precise control over multiple reaction processes without using complex pump, microvalve, and tubing networks. DMF also presents other distinct features, such as portability, less sample consumption, shorter chemical reaction time, flexibility, and easier combination with other technology types. Due to its unique advantages, DMF has been applied to a broad range of fields (e.g., chemistry, biology, medicine, and environment). This study reviews the basic principles of droplet actuation, configuration design, and fabrication of the DMF device, as well as discusses the latest progress in DMF from the biochemistry perspective.

Keywords： digital microfluidics     electrowetting on dielectric     discrete droplet     biochemistry    

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Progress in Study of Standard Room/Corner Fire Test of Lining Materials on Enclosure

Yang Yun,Zhang Heping,Liu Jiyang

Strategic Study of CAE 2003, Volume 5, Issue 4,   Pages 55-60

Abstract: It's mainly used to evaluate lining materials on enclosure.progress in study on fire behavior of linings, which is under this method，including the researches of liningFurthermore, the application of results on the classification and fire hazard evaluation of lining materials

Keywords： lining materials     full-scale     ISO 9705     room/corner fire test    

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Assessment of Mechanical Characteristic for Reinforced Concrete Precast Arc Shaft Lining

Rong Chuanxin,Wang Xiuxi,Cheng Hua

Strategic Study of CAE 2005, Volume 7, Issue 7,   Pages 43-49

Abstract:

Assessment of mechanical characteristic for reinforced concrete precast arc shaft lining is achievedthe same time, the load carrying capacity of the high strength reinforced concrete precast arc shaft liningTherefore for designing the high and strong reinforced concrete precast arc shaft lining, the ratio of

Keywords： high strength reinforced concrete precast arc shaft lining     mechanical characteristic     finite element method    

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Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic peripheral stem cell transplantation for adult patients with lymphoid malignancies: a prospective single-arm phase II study

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 108-115 doi: 10.1007/s11684-019-0730-8

Abstract: Post-transplantation cyclophosphamide (PT-Cy) alone or in combination with other immunosuppressive drugs has emerged as a promising strategy in the setting of allogeneic hematopoietic stem cell transplantation. Improved survival rate was reported in lymphoid malignancies following PT-Cy strategy compared with myeloid disease in non-myeloablative bone marrow transplant setting. Thus, we aimed to evaluate the safety and efficacy of PT-Cy combined with cyclosporine as graft-versus-host disease (GVHD) prophylaxis after myeloablative conditioning and T cell-replete peripheral stem cell transplantation in lymphoid malignancies. This single-arm phase II clinical trial (NCT01435447) involving 31 adult patients was conducted from January 2013 to June 2018. The donor-type neutrophil engraftment rate was 100%, and the overall incidence of grade II to IV and grade III to IV acute GVHD was 39% and 24%, respectively. The cumulative incidence rates of chronic GVHD (35%), including moderate to severe forms (10%), were reduced compared with those of the historical group ( =0.03 and =0.04, respectively). With a median follow-up of 18 months, the estimated 2-year overall and event-free survival was 64.8% (95% confidence interval: 47.8%–86.7%) and 58.4% (95% CI: 41.9%–81.7%), respectively. The 2-year cumulative incidence rate of relapse was 19.5% (95% CI: 9.0%–35.8%), whereas the non-relapse mortality rate was 21.8% (95% CI: 11.3%–38.1%). These results demonstrated the feasibility of PT-Cy as GVHD prophylaxis in this clinical setting. This strategy could significantly reduce the incidence of chronic GVHD and its moderate to severe forms but not of acute GVHD and results in similar survival outcomes compared with the historical group. A prospective study with additional patients is warranted to confirm the role of PT-Cy in lymphoid malignancy.

Keywords： post-transplantation cyclophosphamide     allogeneic hematopoietic stem cell transplantation     lymphoid malignancies    

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Prototype test study on mechanical characteristics of segmental lining structure of underwater railway

He Chuan,Feng Kun,Yan Qixiang,Qi Chun

Strategic Study of CAE 2012, Volume 14, Issue 10,   Pages 65-72

Abstract: Guangzhou Zhujiang River Shiziyang shield tunnel, the prototype test is carried out against its segmental liningAnd the mechanical characteristics of segmental lining structure using straight assembling and staggeredThe results show that the mechanical characteristics of segmental lining structure vary from different

Keywords： underwater railway shield tunnel     segmental lining structure     prototype test     tenon joint     failure characteristics    

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Zinc homeostasis in the metabolic syndrome and diabetes

Xiao Miao, Weixia Sun, Yaowen Fu, Lining Miao, Lu Cai

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 31-52 doi: 10.1007/s11684-013-0251-9

Abstract:

Zinc (Zn) is an essential mineral that is required for various cellular functions. Zn dyshomeostasis always is related to certain disorders such as metabolic syndrome, diabetes and diabetic complications. The associations of Zn with metabolic syndrome, diabetes and diabetic complications, thus, stem from the multiple roles of Zn: (1) a constructive component of many important enzymes or proteins, (2) a requirement for insulin storage and secretion, (3) a direct or indirect antioxidant action, and (4) an insulin-like action. However, whether there is a clear cause-and-effect relationship of Zn with metabolic syndrome, diabetes, or diabetic complications remains unclear. In fact, it is known that Zn deficiency is a common phenomenon in diabetic patients. Chronic low intake of Zn was associated with the increased risk of diabetes and diabetes also impairs Zn metabolism. Theoretically Zn supplementation should prevent the metabolic syndrome, diabetes, and diabetic complications; however, limited available data are not always supportive of the above notion. Therefore, this review has tried to summarize these pieces of available information, possible mechanisms by which Zn prevents the metabolic syndrome, diabetes, and diabetic complications. In the final part, what are the current issues for Zn supplementation were also discussed.

Keywords： zinc     zinc transporters     metallothionein     diabetes     diabetic complications     insulin resistance     antioxidant    

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Research and Development of Inert cathode and Anode in Aluminium Electrolysis

Qiu Zhuxian

Strategic Study of CAE 2001, Volume 3, Issue 5,   Pages 50-54

Abstract: They include inert cathode, inert anode, dipolar electrode and SiC side lining.

Keywords： inert anode     inert cathode     SiC side lining     aluminium electrolysis at lower temperatures    

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Study on water pressure characteristics of Xiamen Xiang’an Subsea Tunnel

Cheng Zhengming

Strategic Study of CAE 2012, Volume 14, Issue 11,   Pages 29-35

Abstract:

The reasonable water pressure upon lining determination is the key toThe analytic method calculation formula of outside pressure upon lining of circular subsea tunnel wasResults of model tests showed that under the condition of fully closed, the pressure on lining couldLining external water pressure formula under limited drainage was established, and it was also verified

Keywords： subsea tunnel     lining     water pressure     model test     limited drainage     reduction    

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Factors influencing the somatic cell nuclear transfer efficiency in pigs

Qiang XIONG, Lihua ZHAO, Xiaowei NIE, Daorong HOU, Qiang LIU, Junzheng WANG, Chenyu WANG, Xiaokang LI, Lining

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 73-80 doi: 10.15302/J-FASE-2018220

Abstract:

Using a data set from our laboratory, we assessed the effects of several factors on pig cloning efficiency. The results demonstrated that cells at high confluence (>90%) used as donor cell resulted in higher pregnancy rate, delivery rate and overall cloning efficiency (number of live offspring born per reconstructed embryo transferred to recipients) compared with the cells at 60% to 79% confluence and 80% to 89% confluence. Cells with four, five and six passages compromised the pregnancy and delivery rates compared with first passage cells. The number of blastocysts transferred by somatic cell nuclear transfer (SCNT) did not significantly affect the cloning efficiency, but transfer of blastocyst derived from culture 5 d after SCNT achieved a significantly higher pregnancy rate compared with one to two cell SCNT embryos from overnight culture. The highest pregnancy rate, delivery rate and the largest litter size were obtained when Bama Miniature pig fibroblasts were used as donor cells and Landrace/Yorkshire hybrid gilts were used as recipients. Recipients treated with chemicals for estrus synchronization had higher pregnancy rates compared with untreated recipients. Our data might be helpful for improving SCNT efficiency in pigs.

Keywords： blastocyst     donor cell     estrus synchronization     pregnancy rate     pig cloning     somatic cell nuclear transfer    

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Large-scale model test study on the water pressure resistance of construction joints of karst tunnel linings

Frontiers of Structural and Civil Engineering   Pages 1249-1263 doi: 10.1007/s11709-023-0974-x

Abstract: adopted based on the New Yuanliangshan tunnel project to investigate the water pressure resistance of liningmodel test was designed and conducted, innovatively transforming the external water pressure of the liningThe results show that using waterstops can significantly improve the water pressure resistance of liningThe water pressure resistance of the lining construction joint is positively correlated with the liningIn addition, the type of waterstop significantly influences the water pressure resistance of lining construction

Keywords： karst tunnel     lining construction joint     water pressure resistance     large-scale model test     numerical    

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Service Security of Underwater Tunnel Lining Structures and Corresponding Guarantee Countermeasures

He Chuan,Liu Sijin,Zhang Yuchun and Feng Kun

Strategic Study of CAE 2017, Volume 19, Issue 6,   Pages 44-51 doi: 10.15302/J-SSCAE-2017.06.007

Abstract:

This paper analyzes four aspects of the safety problems in tunnel liningunderground traffic tunnel in Shanghai was carried out, and the status quo of China’s underwater tunnel lining

Keywords： underwater tunnels     service security     security guarantee countermeasures     long life     structural defects    

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Title Author Date Type Operation

Damage on lining concrete in highway tunnels under combined sulfate and chloride attack

Rongrong YIN, Chenchen ZHANG, Qing WU, Baocheng LI, He XIE

Journal Article

Stress observation of shaft lining wall during construction and initial operation

Wen Dehua

Journal Article

Deep convolutional neural network for multi-level non-invasive tunnel lining assessment

Journal Article

Application of coupled XFEM-BCQO in the structural optimization of a circular tunnel lining subjected

Nazim Abdul NARIMAN, Ayad Mohammad RAMADAN, Ilham Ibrahim MOHAMMAD

Journal Article

Digital microfluidics: A promising technique for biochemical applications

He WANG, Liguo CHEN, Lining SUN

Journal Article

Progress in Study of Standard Room/Corner Fire Test of Lining Materials on Enclosure

Yang Yun,Zhang Heping,Liu Jiyang

Journal Article

Assessment of Mechanical Characteristic for Reinforced Concrete Precast Arc Shaft Lining

Rong Chuanxin,Wang Xiuxi,Cheng Hua

Journal Article

Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic peripheral stem cell transplantation for adult patients with lymphoid malignancies: a prospective single-arm phase II study

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Journal Article

Prototype test study on mechanical characteristics of segmental lining structure of underwater railway

He Chuan,Feng Kun,Yan Qixiang,Qi Chun

Journal Article

Zinc homeostasis in the metabolic syndrome and diabetes

Xiao Miao, Weixia Sun, Yaowen Fu, Lining Miao, Lu Cai

Journal Article

Research and Development of Inert cathode and Anode in Aluminium Electrolysis

Qiu Zhuxian

Journal Article

Study on water pressure characteristics of Xiamen Xiang’an Subsea Tunnel

Cheng Zhengming

Journal Article

Factors influencing the somatic cell nuclear transfer efficiency in pigs

Qiang XIONG, Lihua ZHAO, Xiaowei NIE, Daorong HOU, Qiang LIU, Junzheng WANG, Chenyu WANG, Xiaokang LI, Lining

Journal Article

Large-scale model test study on the water pressure resistance of construction joints of karst tunnel linings

Journal Article

Service Security of Underwater Tunnel Lining Structures and Corresponding Guarantee Countermeasures

He Chuan,Liu Sijin,Zhang Yuchun and Feng Kun

Journal Article